Title :
Maps for visualization and analysis of perfusion
Author :
Pearlman, Justin D. ; Chuang, Michael L. ; Dewagan, Navin
Author_Institution :
Div. of Magnetic Resonance Imaging, Beth Israel Hospital, Boston, MA, USA
Abstract :
A novel method for summarizing and displaying time-series data from magnetic resonance imaging of myocardial perfusion is presented. The method generates a synthetic image or “space-time map” that shows signal intensity as a function of time and position within the heart. The extents of abnormal regions as well as relative and absolute perfusion delays can be measured directly from the space-time maps. Space-time maps were generated from T1-weighted time-series images of myocardial perfusion in 17 Yorkshire pigs with chronic myocardial ischemia. Extents of ischemic and infarct regions as determined from space-time maps by two independent observers correlated well (r=0.93 and 0.97 respectively). The space-time mapping concept can be applied to time-series image data from other sources
Keywords :
biomedical NMR; blood flow measurement; cardiology; haemorheology; medical image processing; muscle; nuclear spin-lattice relaxation; time series; MRI time-series data; T1-weighted time-series images; Yorkshire pigs; absolute perfusion delay; chronic myocardial ischemia; infarcted region; ischemic region; magnetic resonance imaging; medical diagnostic imaging; myocardial perfusion; perfusion analysis; perfusion visualization; relative perfusion delay; signal intensity; space-time maps; Animals; Biomedical engineering; Heart; Hospitals; Image generation; Ischemic pain; Magnetic analysis; Magnetic resonance imaging; Myocardium; Visualization;
Conference_Titel :
Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference
Conference_Location :
Montreal, Que.
Print_ISBN :
0-7803-2475-7
DOI :
10.1109/IEMBS.1995.575213
