Fluorescence imaging using transport-theory-based imaging operators

Author

Chang, Jenghwa ; Graber, Harry ; Aronson, Raphael ; Barbour, Randall L.

Author_Institution

Dept. of Pathol., SUNY Health Sci. Center, Brooklyn, NY, USA

Volume

1

fYear

1995

fDate

20-25 Sep 1995

Firstpage

515

Abstract

We derive a linear operator, based on transport theory, for imaging fluorophore concentrations. The elements of the weight matrix of the resulting system are calculated from results of Monte Carlo simulations. Experimental data were collected by irradiating a cylindrical phantom containing two fluorophore-filled balloons with laser light. The reconstruction results show that good quality images can be obtained with both embedded objects accurately located

Keywords

Monte Carlo methods; biomedical imaging; fluorescence; image reconstruction; laser applications in medicine; light propagation; medical image processing; optical tomography; CT-type scanning laser system; Monte Carlo simulations; cylindrical phantom; embedded objects; fluorescence imaging; fluorophore concentrations; fluorophore-filled balloons; good quality images; laser light; linear operator; optical imaging; physiological states; reconstruction results; transport-theory-based imaging operators; weight matrix elements; Detectors; Equations; Fluorescence; Image reconstruction; Imaging phantoms; Laser theory; Optical imaging; Optical propagation; Physiology; Probes;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference

Conference_Location

Montreal, Que.

Print_ISBN

0-7803-2475-7

Type

conf

DOI

10.1109/IEMBS.1995.575227

Filename

575227