Characterisation of heart rate changes and their correlation with EEG during neonatal seizures

Author

Doyle, O.M. ; Greene, B.R. ; Marnane, W. ; Lightbody, G. ; Boylan, G.B.

Author_Institution

Neonatal Brain research group, University College Cork, Ireland

fYear

2008

fDate

20-25 Aug. 2008

Firstpage

4984

Lastpage

4987

Abstract

The effect of seizures on instantaneous HR (iHR) in 12 neonates is investigated here. HR can be readily extracted from the ECG and can be employed as an additional signal in seizure detection algorithms. The change in instantaneous HR and its correlation with the change in RMS EEG amplitude were examined. Two methods were employed to classify significant iHR changes. Significant correlation (p < 0.05) during seizure was observed in 100% of patients (83.33% of seizures). Overall, significant iHR changes (classified by either method) were found in 83% of patients (50% of seizures). It was found that a markedly higher iHR was observed in patients whose seizures were not classified as having significant iHR changes.

Keywords

Biomedical measurements; Detection algorithms; Educational institutions; Electrocardiography; Electroencephalography; Event detection; Heart rate; Patient monitoring; Pediatrics; Signal detection; ECG; EEG; Neonatal; heart rate; seizure; Diagnosis, Computer-Assisted; Electrocardiography; Electroencephalography; Female; Heart Rate; Humans; Infant, Newborn; Male; Neonatal Screening; Reproducibility of Results; Seizures; Sensitivity and Specificity; Statistics as Topic;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2008. EMBS 2008. 30th Annual International Conference of the IEEE

Conference_Location

Vancouver, BC

ISSN

1557-170X

Print_ISBN

978-1-4244-1814-5

Electronic_ISBN

1557-170X

Type

conf

DOI

10.1109/IEMBS.2008.4650333

Filename

4650333