DocumentCode :
3084853
Title :
Nucleotide Fluctuation Analysis of Dim-Light Vision Rhodopsin Gene and mRNA Sequences in Vertebrates
Author :
Holden, Todd ; Gadura, N. ; Cheung, E. ; Rada, J. ; Schneider, P. ; Tremberger, G., Jr. ; Sunil, D. ; Lieberman, D. ; Cheung, T.
Author_Institution :
Phys. Dept., CUNY, Bayside, NY, USA
fYear :
2010
fDate :
18-20 June 2010
Firstpage :
1
Lastpage :
4
Abstract :
Fractal dimension and Shannon entropy were used to analyze the nucleotide fluctuation of dim-light vision rhodopsin gene. The maximal absorption wavelengths of the studied gene sequences span a range of 480 nm to 526 nm. The di-nucleotide Shannon entropy correlates with (a) the mono-nucleotide Shannon entropy with R2 of 0.99; (b) the CG+GC content with R2 of 0.86 (N = 6). The absorption maximal wavelength correlation with the CG+GC content was found to have an R2 of 0.82 for the gene sequence and 0.91 for the mRNA sequence. The fractal dimensions of the gene sequences and mRNA sequences were found to be correlated with R2 of 0.78. Selection pressure on the CG+GC content at the gene and mRNA levels would be a consistent observation for phenotype dim-light functionality.
Keywords :
biological techniques; biology computing; entropy; genetics; molecular biophysics; molecular configurations; CG+GC content; absorption maximal wavelength correlation; dim-light vision rhodopsin gene sequence; fractal dimension; mRNA levels; mRNA sequence; maximal absorption wavelengths; mononucleotide Shannon entropy; nucleotide fluctuation analysis; phenotype dim-light functionality; vertebrates; Absorption; Acceleration; Bioinformatics; Entropy; Fluctuations; Fractals; Genomics; Humans; Protons; Sequences;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
Conference_Location :
Chengdu
ISSN :
2151-7614
Print_ISBN :
978-1-4244-4712-1
Electronic_ISBN :
2151-7614
Type :
conf
DOI :
10.1109/ICBBE.2010.5514714
Filename :
5514714
Link To Document :
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