• DocumentCode
    3084853
  • Title

    Nucleotide Fluctuation Analysis of Dim-Light Vision Rhodopsin Gene and mRNA Sequences in Vertebrates

  • Author

    Holden, Todd ; Gadura, N. ; Cheung, E. ; Rada, J. ; Schneider, P. ; Tremberger, G., Jr. ; Sunil, D. ; Lieberman, D. ; Cheung, T.

  • Author_Institution
    Phys. Dept., CUNY, Bayside, NY, USA
  • fYear
    2010
  • fDate
    18-20 June 2010
  • Firstpage
    1
  • Lastpage
    4
  • Abstract
    Fractal dimension and Shannon entropy were used to analyze the nucleotide fluctuation of dim-light vision rhodopsin gene. The maximal absorption wavelengths of the studied gene sequences span a range of 480 nm to 526 nm. The di-nucleotide Shannon entropy correlates with (a) the mono-nucleotide Shannon entropy with R2 of 0.99; (b) the CG+GC content with R2 of 0.86 (N = 6). The absorption maximal wavelength correlation with the CG+GC content was found to have an R2 of 0.82 for the gene sequence and 0.91 for the mRNA sequence. The fractal dimensions of the gene sequences and mRNA sequences were found to be correlated with R2 of 0.78. Selection pressure on the CG+GC content at the gene and mRNA levels would be a consistent observation for phenotype dim-light functionality.
  • Keywords
    biological techniques; biology computing; entropy; genetics; molecular biophysics; molecular configurations; CG+GC content; absorption maximal wavelength correlation; dim-light vision rhodopsin gene sequence; fractal dimension; mRNA levels; mRNA sequence; maximal absorption wavelengths; mononucleotide Shannon entropy; nucleotide fluctuation analysis; phenotype dim-light functionality; vertebrates; Absorption; Acceleration; Bioinformatics; Entropy; Fluctuations; Fractals; Genomics; Humans; Protons; Sequences;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
  • Conference_Location
    Chengdu
  • ISSN
    2151-7614
  • Print_ISBN
    978-1-4244-4712-1
  • Electronic_ISBN
    2151-7614
  • Type

    conf

  • DOI
    10.1109/ICBBE.2010.5514714
  • Filename
    5514714