DocumentCode :
3086332
Title :
Cortical recording with polypyrrole microwire electrodes
Author :
Bae, Woong J. ; Ruddy, Bryan P. ; Richardson, Andrew G. ; Hunter, Ian W. ; Bizzi, Emilio
Author_Institution :
Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, 02139 USA
fYear :
2008
fDate :
20-25 Aug. 2008
Firstpage :
5794
Lastpage :
5797
Abstract :
The ability to record from the same neuron for extended periods of time is essential to understanding how the brain reorganizes during learning. Conventional chronic recording microelectrodes are made from metal or silicon. However, the large stiffness mismatch between the electrodes and brain tissue causes shear-induced inflammation, limiting long-term recording stability. The flexibility of polypyrrole microwire has the potential to improve the chronic recording stability by minimizing the stiffness mismatch. In this paper, we report the implantation of a conducting polymer microwire electrode in a rodent brain, and the successful recording of cortical activity using such an electrode.
Keywords :
Biological materials; Brain; Conducting materials; Electrodes; Mechanical factors; Neurons; Polymers; Probes; Silicon; Stability; Action Potentials; Animals; Cerebral Cortex; Computer-Aided Design; Electrodes, Implanted; Electroencephalography; Equipment Design; Equipment Failure Analysis; Microelectrodes; Miniaturization; Polymers; Pyrroles; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Engineering in Medicine and Biology Society, 2008. EMBS 2008. 30th Annual International Conference of the IEEE
Conference_Location :
Vancouver, BC
ISSN :
1557-170X
Print_ISBN :
978-1-4244-1814-5
Electronic_ISBN :
1557-170X
Type :
conf
DOI :
10.1109/IEMBS.2008.4650531
Filename :
4650531
Link To Document :
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