Title :
Efficient solutions of cardiac membrane models using novel unsupervised clustering algorithm
Author :
Hussan, Jagir R. ; Trew, Mark L. ; Hunter, Peter J.
Author_Institution :
Auckland Bioengineering Institute, University of Auckland, New Zealand
Abstract :
We present a method to efficiently solve cardiac membrane models using a novel unsupervised clustering algorithm. The unsupervised clustering algorithm was designed to handle repeated clustering of multidimensional objects with rapidly changing properties. A Modified Trie datastructure that allowed efficient search, scalable and distributed assembly of the result was designed. The method was applied to solve monodomain models of cardiac tissue with highly non-linear reaction elements. We demonstrate the versatility and advantages of using the method by subjecting the tissue to various spatial excitation patterns.
Keywords :
Assembly; Biomembranes; Cardiac tissue; Cells (biology); Clustering algorithms; Computational modeling; Equations; Multidimensional systems; Virtual manufacturing; Voltage; Cardiac Action potential; Numerical Solutions; Reaction-Diffusion; Unsupervised Clustering; Action Potentials; Animals; Artificial Intelligence; Cell Membrane; Cluster Analysis; Computer Simulation; Heart Conduction System; Humans; Membrane Potentials; Models, Cardiovascular;
Conference_Titel :
Engineering in Medicine and Biology Society, 2008. EMBS 2008. 30th Annual International Conference of the IEEE
Conference_Location :
Vancouver, BC
Print_ISBN :
978-1-4244-1814-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2008.4650560