DocumentCode
3094569
Title
Acute Toxicity Study of Naphthaquinones Exposure to Chlorella pyrenoidosa
Author
Guo, Jing ; Song, Wenhua ; Ding, Feng ; Li, Liying ; Zhang, Jinghua ; Lian, Jie ; Li, Zhen
Author_Institution
Sch. of Environ. & Chem. Eng., Tianjin Polytech. Univ., Tianjin, China
fYear
2010
fDate
18-20 June 2010
Firstpage
1
Lastpage
4
Abstract
In this paper, five naphthaquinones were regarded as research objects. The acute growth inhibition toxicities of naphthaquinones on Chlorella pyrenoidosa at 72h, expressed as median inhibit concentration (EC50) were determined. The results showed that these naphthaquinones were harmful, toxic and very toxic to C. pyrenoidosa. The active positions of these naphthoquinones acting on the biomacromolecule of C. pyrenoidosa maybe were 1-carbonyl and 2-alkyl of naphthoquinone via hydrogen bond and hydrophobic interaction. This study laid a foundation to evaluate the aquatic ecological risk and toxicology mechanism of naphthaquinones to C. pyrenoidosa.
Keywords
biotechnology; macromolecules; microorganisms; toxicology; water pollution; acute toxicity; aquatic ecological risk; biomacromolecule; chlorella pyrenoidosa; hydrophobic interaction; naphthaquinones exposure; time 72 h; Acquired immune deficiency syndrome; Bonding; Chemical engineering; Content addressable storage; Drugs; Hydrogen; Manufacturing; Organisms; Testing; Toxicology;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
Conference_Location
Chengdu
ISSN
2151-7614
Print_ISBN
978-1-4244-4712-1
Electronic_ISBN
2151-7614
Type
conf
DOI
10.1109/ICBBE.2010.5515174
Filename
5515174
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