DocumentCode :
3096605
Title :
Effects of Aluminum Exposure on Antioxidative Activity and Humoral Immune Function in Chickens: Preliminary Study of Aluminum Accumulation on Immune System in Chickens
Author :
Zhao Han-Song ; Li Yan-fei ; Liu Fu-Tang ; Liu Yun-Feng
Author_Institution :
Coll. of Veterinary Med., Northeast Agric. Univ., Harbin, China
fYear :
2010
fDate :
18-20 June 2010
Firstpage :
1
Lastpage :
4
Abstract :
The activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and concentrations of malondialdehyde (MAD) in serum, spleen and bursa of Fabricius and the concentrations of Immunoglobulin G (IgG) , Immunoglobulin A (IgA), Immunoglobulin M (IgM) and HI antibody titer to Newcastle Disease in serum were detected in chickens with different levels sub-chronic aluminum (Al) intoxication produced by continuous peritoneal injection of various gradient aluminum trichloride (AlCl3). The results showed that the concentrations of MDA in chickens were higher and other indexes were lower in the experimental groups than in the control group. There was significantly different (P<;0.05 or P<;0.01) between groups, dose-effect relationship between with AlCl3. The results indicate that Al exposure inhibits the antioxidative activity and humoral immune function in chickens.
Keywords :
agriculture; biochemistry; enzymes; molecular biophysics; toxicology; HI antibody; Newcastle Disease; antioxidative activity; bursa of Fabricius; chickens; dose-effect relationship; glutathione peroxidase; humoral immune function; immunoglobulin A; immunoglobulin G; immunoglobulin M; malondialdehyde; serum; spleen; subchronic aluminum intoxication; superoxide dismutase; Aluminum; Animals; Diseases; Earth; Educational institutions; Immune system; Inorganic materials; Medical diagnostic imaging; Medical treatment; Metals industry;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
Conference_Location :
Chengdu
ISSN :
2151-7614
Print_ISBN :
978-1-4244-4712-1
Electronic_ISBN :
2151-7614
Type :
conf
DOI :
10.1109/ICBBE.2010.5515287
Filename :
5515287
Link To Document :
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