Title :
A nano emulsion generator using a microchannel and a bolt blamped type transducer
Author :
Kanda, Takefumi ; Kiyama, Yusuke ; Suzumori, Koichi
Author_Institution :
Grad. Sch. of Natural Sci. & Technol., Okayama Univ., Okayama, Japan
Abstract :
The goal of this research is to generate antitumor substance emulsion which has a droplets´ diameter of 200 nm or less. In our previous study, a microchannel device was oscillated by 2.3 MHz plate type vibrator. In this study, a small bolt clamped type transducer has been designed and fabricated to apply higher pressure against the micron-size droplets. The cross sectional pattern of the ultrasonic microchannel device and the bolt clamped type transducer was designed by using FEM. By using the device, we have succeeded in generating nano emulsion and the peak of diameter was in 100 nm.
Keywords :
bioMEMS; biomedical materials; biomedical transducers; biomedical ultrasonics; drops; emulsions; finite element analysis; microchannel flow; microfabrication; nanofabrication; nanomedicine; tumours; vibrations; antitumor substance; bolt clamped type transducer; finite element method; frequency 2.3 MHz; micron-size droplets; nanoemulsion generator; plate type vibrator; size 100 nm; size 200 nm; ultrasonic microchannel device; Admittance; Finite element analysis; Nanoscale devices; Size measurement; Transducers; Bolt clamped type transducer; Microchannel; Nano emulsion; Piezoelectric vibrator;
Conference_Titel :
Ultrasonics Symposium (IUS), 2013 IEEE International
Conference_Location :
Prague
Print_ISBN :
978-1-4673-5684-8
DOI :
10.1109/ULTSYM.2013.0050
