RSNA/QIBA: Shear wave speed as a biomarker for liver fibrosis staging

Author

Hall, Trevor J. ; Milkowski, Andy ; Garra, Brian ; Carson, Paul ; Palmeri, Mark ; Nightingale, Kathryn ; Lynch, Ted ; Alturki, Abdullah ; Andre, M. ; Audiere, Stephane ; Bamber, Jeffrey ; Barr, R. ; Bercoff, Jeremy ; Bercoff, Jeremy ; Bernal, Miguel ; Bru

Author_Institution

Med. Phys. Dept., Univ. of Wisconsin, Madison, WI, USA

fYear

2013

fDate

21-25 July 2013

Firstpage

397

Lastpage

400

Abstract

An interlaboratory study of shear wave speed (SWS) estimation was performed. Commercial shear wave elastography systems from Fibroscan, Philips, Siemens and Supersonic Imagine, as well as several custom laboratory systems, were involved. Fifteen sites were included in the study. CIRS manufactured and donated 11 pairs of custom phantoms designed for the purposes of this investigation. Dynamic mechanical tests of equivalent phantom materials were also performed. The results of this study demonstrate that there is very good agreement among SWS estimation systems, but there are several sources of bias and variance that can be addressed to improve consistency of measurement results.

Keywords

biomechanics; biomedical ultrasonics; diseases; dynamic testing; elastic waves; liver; phantoms; ultrasonic imaging; Fibroscan; Philips; RSNA-QIBA; Siemens; Supersonic Imagine; biomarker; commercial shear wave elastography systems; custom phantoms; dynamic mechanical testing; equivalent phantom materials; liver fibrosis staging; shear wave speed estimation; Current measurement; Educational institutions; Liver; Materials; Phantoms; Ultrasonic imaging;

fLanguage

English

Publisher

ieee

Conference_Titel

Ultrasonics Symposium (IUS), 2013 IEEE International

Conference_Location

Prague

ISSN

1948-5719

Print_ISBN

978-1-4673-5684-8

Type

conf

DOI

10.1109/ULTSYM.2013.0103

Filename

6725226