Virtual Microscopy and Analysis Using Scientific Workflows

Author

Abramson, David ; Bethwaite, Blair ; Dinh, Minh Ngoc ; Enticott, Colin ; Firth, Stephen ; Garic, Slavisa ; Harper, Ian ; Lackmann, Martin ; Nguyen, Hoang ; Ramdas, Tirath ; Russel, A.B.M. ; Schek, Stefan ; Vail, Mary

Author_Institution

Fac. of Inf. Technol., Monash Univ., Clayton, VIC, Australia

fYear

2009

fDate

9-11 Dec. 2009

Firstpage

239

Lastpage

246

Abstract

Most commercial microscopes are stand-alone instruments, controlled by dedicated computer systems. These provide limited storage and processing capabilities. Virtual microscopes, on the other hand, link the image capturing hardware and data analysis software into a wide area network of high performance computers, large storage devices and software systems. In this paper we discuss extensions to Grid workflow engines that allow them to execute scientific experiments on virtual microscopes. We demonstrate the utility of such a system in a biomedical case study concerning the imaging of cancer and antibody based therapeutics.

Keywords

cancer; data analysis; grid computing; medical image processing; microscopes; storage management; virtual instrumentation; workflow management software; antibody based therapeutics; biomedical case study; cancer imaging; commercial microscopes; data analysis software; dedicated computer systems; grid workflow engines; high performance computers; image capturing hardware; large storage devices; scientific experiments; scientific workflows; software systems; stand-alone instruments; virtual microscopy; wide area network; Biomedical computing; Computer networks; Control systems; Data analysis; Hardware; Image storage; Instruments; Microscopy; Software performance; Wide area networks; Grid Computing; Virtual Instruments;

fLanguage

English

Publisher

ieee

Conference_Titel

e-Science, 2009. e-Science '09. Fifth IEEE International Conference on

Conference_Location

Oxford

Print_ISBN

978-0-7695-3877-8

Type

conf

DOI

10.1109/e-Science.2009.41

Filename

5380862