Title :
Combining Optical Imaging and Computational Modeling to Analyze Structure and Function of Living Neurons
Author :
Losavio, Bradley E. ; Reddy, G. Duemani ; Colbert, Costa M. ; Kakadiaris, Ioannis A. ; Saggau, Peter
Author_Institution :
Dept. of Neurosci., Baylor Coll. of Med., Houston, TX
fDate :
Aug. 30 2006-Sept. 3 2006
Abstract :
We are investigating the computational properties of principal neurons in the mammalian brain. To manage the small size and intricate structure of neuronal dendrites, we employ advanced optical imaging techniques in combination with automatic image reconstruction and computational modeling to study their complex spatio-temporal pattern of activity
Keywords :
biomedical optical imaging; brain; cellular biophysics; image reconstruction; medical image processing; neurophysiology; spatiotemporal phenomena; automatic image reconstruction; computational modeling; mammalian brain; neuronal dendrite structure; optical imaging technique; spatio-temporal pattern; Brain; Computational modeling; Fluorescence; Image analysis; Image reconstruction; Neurons; Optical computing; Optical imaging; Optical microscopy; Particle beam optics;
Conference_Titel :
Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE
Conference_Location :
New York, NY
Print_ISBN :
1-4244-0032-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2006.259552
