Title :
Localized surface plasmon coupled fluorescence fiber-optic biosensor for severe acute respiratory syndrome coronavirus nucleocapsid protein detection
Author :
Chang, Ying-Feng ; Huang, Jason C. ; Su, Li-Chen ; Chen, Yi-Ming Arthur ; Chen, Chii-Chang ; Chou, Chien
Author_Institution :
Inst. of Biophotonics, Nat. Yang-Ming Univ., Taipei, Taiwan
Abstract :
Detection of severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in human serum using localized surface plasmon coupled fluorescence (LSPCF) fiber-optic biosensor. The detection limit at 1 pg/mL in human serum is successfully demonstrated.
Keywords :
biosensors; fibre optic sensors; fluorescence; proteins; surface plasmons; LSPCF fiber-optic biosensor; SAR coronavirus nucleocapsid protein detection; human serum; localized surface plasmon coupled fluorescence; severe acute respiratory syndrome; Biosensors; Fluorescence; Humans; Immune system; Optical coupling; Optical surface waves; Plasmons; Probes; Proteins; Surface cleaning;
Conference_Titel :
OptoElectronics and Communications Conference, 2009. OECC 2009. 14th
Conference_Location :
Hong Kong
Print_ISBN :
978-1-4244-4102-0
Electronic_ISBN :
978-1-4244-4103-7
DOI :
10.1109/OECC.2009.5215723
