Title :
Exploring the mechanics of endothelial cells one cell at a time
Author_Institution :
Dept. of Mech. Eng., MIT, Boston, MA, USA
Abstract :
Summary form only given. Research during the past 20 years on the biology of the vascular wall, and the endothelial layer lining the major arteries in particular, has been dominated by measurements and theories that treat the layer as being homogeneous. This is not the case, and more recent measurements have shown that the behavior of individual cells can differ markedly from the mean. In this address, I will review some of the new results that provide information at the level of individual cells and suggest how these differences between cells can provide clues regarding the biophysical processes that are at work.
Keywords :
biomechanics; blood vessels; cellular biophysics; reviews; 20 y; biophysical processes; endothelial cells mechanics exploring; endothelial layer; homogeneous layer; individual cells behavior; major arteries; Arteries; Biology; Cells (biology); Mechanical engineering; Mechanical variables measurement; Particle measurements;
Conference_Titel :
Molecular, Cellular and Tissue Engineering, 2002. Proceedings of the IEEE-EMBS Special Topic Conference on
Print_ISBN :
0-7803-7557-2
DOI :
10.1109/MCTE.2002.1174983
