Detection of Lung Cancer with Phase-Contrast X-ray Imaging Using Synchrotron Radiation

Author

Liu, Ping ; Sun, Jianqi ; Guan, Yijing ; Zhang, Guilin ; Xu, Lisa Xuemin

Author_Institution

Sch. of Life Sci. & Technol., Shanghai Jiao Tong Univ.

fYear

2006

fDate

Aug. 30 2006-Sept. 3 2006

Firstpage

2001

Lastpage

2004

Abstract

In the present study, the feasibility of applying synchrotron radiation for the detection of lung cancers was investigated. Lung cancer tissues grown in mice over different periods were observed with phase-contrast synchrotron X-ray chest imaging. Irregular and tortuous vessels appearing in early cancer angiogenesis were found in the periphery region of the implanted cancer. Structure difference was clearly shown between normal tissue and early stage solid cancer in micrometers. Results from this study indicate that synchrotron X-ray may open broad perspectives for imaging cancer development and progression noninvasively

Keywords

cancer; diagnostic radiography; lung; synchrotron radiation; tumours; angiogenesis; chest imaging; lung cancer tissue detection; mice; phase-contrast X-ray imaging; synchrotron radiation; tortuous vessel; Cancer detection; Lungs; Mice; Optical imaging; Phase detection; Radiation detectors; Synchrotron radiation; X-ray detection; X-ray detectors; X-ray imaging;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE

Conference_Location

New York, NY

ISSN

1557-170X

Print_ISBN

1-4244-0032-5

Electronic_ISBN

1557-170X

Type

conf

DOI

10.1109/IEMBS.2006.260802

Filename

4462176