DocumentCode
3117788
Title
Microfluidic bischemical analysis system
Author
Anderson, Rolfe C. ; Bogdan, Gregory J. ; Bamiv, Zuri ; Dawes, Timothy D. ; Winkler, James ; Roy, Kajal
Author_Institution
Affymetrix Inc., Santa Clara, CA, USA
Volume
1
fYear
1997
fDate
16-19 Jun 1997
Firstpage
477
Abstract
We have developed a genetic-analysis system that integrates all reactions necessary to process a sample and use a microfabricated GeneChip(R) polynucleotide array. This system has performed a multistep assay for monitoring mutations in the HIV virus in 10 μL reaction volumes. The microfluidic structures and thermal control methods demonstrated in this work can be generally applied to integrate other chemical and biochemical analysis systems
Keywords
biological techniques; chemical analysis; chemical reactions; proteins; HIV virus; biochemical analysis; genetic-analysis; hybridisation; integrated reactors; microfabricated GeneChip(R) polynucleotide array; microfluidic bischemical analysis; microfluidic structures; multistep assay; mutations; thermal control; Automatic testing; Biochemical analysis; Chemical analysis; Control systems; Costs; Genetics; Inductors; Lab-on-a-chip; Microfluidics; Monitoring;
fLanguage
English
Publisher
ieee
Conference_Titel
Solid State Sensors and Actuators, 1997. TRANSDUCERS '97 Chicago., 1997 International Conference on
Conference_Location
Chicago, IL
Print_ISBN
0-7803-3829-4
Type
conf
DOI
10.1109/SENSOR.1997.613690
Filename
613690
Link To Document