Title :
Simulation of electromagnetic fields in a microelectrode array
Author :
Oakley, By Barbara ; De Hagen, Julie ; Hanna, Darrin ; Al-Khateeb, Bash ; Al-Nsour, Mahmoud
Author_Institution :
Sch. of Eng. & Comput. Sci., Oakland Univ., Rochester, MI, USA
Abstract :
An area of significant potential in Micro-Electro-Mechanical Systems (MEMS)-related technology is the construction of microelectrode arrays that can be used to preferentially kill nearby biological cells while leaving cells more distant from the array intact. This paper details some of the basic considerations related to this research area, and goes on to explore electromagnetic field strength and its spatial variation around a simple simulated microelectrode array near a biological medium with δ and ε characteristics similar to that of human blood. Simulations were conducted at maximum field strengths of |1.1| volts at a frequency of 100 kHz and 1 MHz.
Keywords :
arrays; biological effects of fields; biomedical electrodes; blood; cellular effects of radiation; microelectrodes; micromechanical devices; physiological models; 1 MHz; 1.1 V; 100 kHz; MEMS; biological medium; electromagnetic fields simulation; human blood; maximum field strength; micro-electro-mechanical systems-related technology; preferential cell killing; simple simulated microelectrode array; spatial variation; Biological system modeling; Blood; Electrodes; Electromagnetic fields; Geometry; Gold; Microelectrodes; Solid modeling; Space vector pulse width modulation; Strips;
Conference_Titel :
Molecular, Cellular and Tissue Engineering, 2002. Proceedings of the IEEE-EMBS Special Topic Conference on
Print_ISBN :
0-7803-7557-2
DOI :
10.1109/MCTE.2002.1175030
