Simulation of electromagnetic fields in a microelectrode array

Author

Oakley, By Barbara ; De Hagen, Julie ; Hanna, Darrin ; Al-Khateeb, Bash ; Al-Nsour, Mahmoud

Author_Institution

Sch. of Eng. & Comput. Sci., Oakland Univ., Rochester, MI, USA

fYear

2002

fDate

2002

Firstpage

111

Lastpage

112

Abstract

An area of significant potential in Micro-Electro-Mechanical Systems (MEMS)-related technology is the construction of microelectrode arrays that can be used to preferentially kill nearby biological cells while leaving cells more distant from the array intact. This paper details some of the basic considerations related to this research area, and goes on to explore electromagnetic field strength and its spatial variation around a simple simulated microelectrode array near a biological medium with δ and ε characteristics similar to that of human blood. Simulations were conducted at maximum field strengths of |1.1| volts at a frequency of 100 kHz and 1 MHz.

Keywords

arrays; biological effects of fields; biomedical electrodes; blood; cellular effects of radiation; microelectrodes; micromechanical devices; physiological models; 1 MHz; 1.1 V; 100 kHz; MEMS; biological medium; electromagnetic fields simulation; human blood; maximum field strength; micro-electro-mechanical systems-related technology; preferential cell killing; simple simulated microelectrode array; spatial variation; Biological system modeling; Blood; Electrodes; Electromagnetic fields; Geometry; Gold; Microelectrodes; Solid modeling; Space vector pulse width modulation; Strips;

fLanguage

English

Publisher

ieee

Conference_Titel

Molecular, Cellular and Tissue Engineering, 2002. Proceedings of the IEEE-EMBS Special Topic Conference on

Print_ISBN

0-7803-7557-2

Type

conf

DOI

10.1109/MCTE.2002.1175030

Filename

1175030