Title :
Nitrobenzene Induces DNA Damage in Tobacco
Author :
Guo Changhong ; Cao Yuwei ; Li Rui ; Si Liang ; Ma Jun ; Yuan Zening
Author_Institution :
Dept. of Biol., Harbin Normal Univ., Harbin, China
Abstract :
Single-cell gel electrophoresis (SCGE) is a useful technical tool to detect DNA damages. In this work, tobacco plants (Nicotiana tabacum var. xanthi) were cultivated in different concentrations of nitrobenzene, and the DNA damages were analyzed by using SCGE. The results showed that the DNA damages increased with increasing nitrobenzene concentrations. Results of the present study suggest that nitrobenzene is one of genotoxic pollutan and may be a genotoxdic risk to human health.
Keywords :
DNA; air pollution; biological techniques; botany; electrophoresis; molecular biophysics; molecular configurations; organic compounds; DNA damage detection; Nicotiana tabacum var. xanthi; SCGE; genotoxic pollutant; nitrobenzene induced DNA damage; single cell gel electrophoresis; tobacco plants; Animals; DNA; Electrokinetics; Humans; Ice; Laboratories; Organisms; Pollution measurement; Postal services; Reactive power;
Conference_Titel :
Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
Conference_Location :
Chengdu
Print_ISBN :
978-1-4244-4712-1
Electronic_ISBN :
2151-7614
DOI :
10.1109/ICBBE.2010.5516350