• DocumentCode
    3120904
  • Title

    Synthesis of Novel Glycyrrhetinic Acid Analogues

  • Author

    Meng, Yan-Qiu ; Wang, Xiang-Lei ; Song, Yan-Ling ; Li, Feng-Qing

  • Author_Institution
    Dept. of Pharm. Eng., Shenyang Univ. of Chem. Technol., Shenyang, China
  • fYear
    2010
  • fDate
    18-20 June 2010
  • Firstpage
    1
  • Lastpage
    4
  • Abstract
    Glycyrrhetinic acid (GA, 3 β-hydroxyl-11-oxo-olean-12-ene-29-oic acid, 1) isolated from Glycyrrhiza glabra was found to have several pharmacological activities. A series of novel GA derivatives were designed and synthesized as antitumor agents. Their structures were confirmed using MS and 1H-NMR.
  • Keywords
    biomedical NMR; botany; cancer; drugs; molecular biophysics; tumours; 1H-NMR; GA derivatives; Glycyrrhiza glabra; MS; antitumor agents; glycyrrhetinic acid analogues; pharmacological activities; Cancer; Cells (biology); Chemical technology; Clouds; Design engineering; Electrons; Petroleum; Pharmaceuticals; Protons; Temperature;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
  • Conference_Location
    Chengdu
  • ISSN
    2151-7614
  • Print_ISBN
    978-1-4244-4712-1
  • Electronic_ISBN
    2151-7614
  • Type

    conf

  • DOI
    10.1109/ICBBE.2010.5516432
  • Filename
    5516432
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=3120904