An Independent Homology Analysis Method in Compound Pyramid Model

Protein secondary structure prediction plays an important role in protein engineering. But its accuracy has not been improved dramatically in recent years and many methods rely on servers to get first data. So an independent homology analysis method is proposed. Besides, this method is successfully applied to the homology analysis module located at comprehensive layer in our compound pyramid model and get better results in our experiment comparing with other methods. The accuracy of the prediction is 83.06% on the RS126 data set and 80.49% on the CB513 data set.