Signal transduction ability measurement of signaling pathways in intracellular communication via fuzzy method

Signal transduction plays an important role in biological organisms. Here, we proposed a method to access the information of the signal transduction ability of signal transduction pathway in the cells. Due to the nonlinear signal transduction pathway model, we have to solve the Hamilton-Jacobi inequalities (HJIs) to get the measurement. Instead of directly solving HJIs, fuzzy interpolation method was employed such that we can systematically measure signal transduction ability by solving the linear matrix inequalities (LMIs). The measurement will provide an insight to the characteristics of the signal transduction networks.