Title :
Photonic crystal fiber based antibody detection
Author :
Duval, A. ; Lhoutellier, M. ; Jensen, J.B. ; Hoiby, P.E. ; Missier, V. ; Pedersen, L.H. ; Hansen, T.P. ; Bjarklev, A. ; Bang, O.
Author_Institution :
Res. Center COM, DTU, Lyngby, Denmark
Abstract :
An original approach for detecting labeled antibodies based on strong penetration photonic crystal fibers is introduced. The target antibody is immobilized inside the air-holes of a photonic crystal fiber and the detection is realized by the means of evanescent-wave fluorescence spectroscopy and the use of a transversal illumination setup.
Keywords :
biosensors; fibre optic sensors; fluorescence spectroscopy; antibody detection; evanescent-wave fluorescence spectroscopy; labeled antibodies; strong penetration photonic crystal fibers; transversal illumination; Biomedical optical imaging; Biosensors; Coatings; Fluorescence; Lattices; Optical fiber sensors; Optical fibers; Photonic crystal fibers; Silicon compounds; Spectroscopy;
Conference_Titel :
Sensors, 2004. Proceedings of IEEE
Print_ISBN :
0-7803-8692-2
DOI :
10.1109/ICSENS.2004.1426399
