DocumentCode :
3124554
Title :
Photodynamic Effects of Quantum Dots on Inactivation of Leukemic HL60 Cells in vitro
Author :
Wang, Huzhong ; Zhang, Haiping ; Xiao, Hua ; Xiong, Jianwen
Author_Institution :
Sch. of Phys. & Telecommun. Eng., South China Normal Univ., Guangzhou, China
fYear :
2010
fDate :
18-20 June 2010
Firstpage :
1
Lastpage :
3
Abstract :
Photosensitization of quantum dots was activated with a LED light source (410nm) delivered at 5mw/cm2 to give a different dose by altering the radiation period. Cellular proliferative activity and apoptosis was measured using the cell counting kit-8 (CCK-8) assay. After four hours following photodynamic treatment, the degree of apoptosis was significantly increased, and the best experimental parameters of inactivation of leukemic HL60 cells in vitro, 2.0×10-6 mol/l (the concentration of QDs), 18J/cm2 (the radiation dose), were obtained.
Keywords :
blood; cancer; cellular biophysics; photodynamic therapy; quantum dots; LED light source; apoptosis; cell counting kit-8 assay; cellular proliferative activity; in vitro leukemic HL60 cell inactivation; photodynamic effects; photosensitization; quantum dots; radiation dose; Biomedical optical imaging; Design for experiments; In vitro; Length measurement; Light emitting diodes; Light sources; Optical materials; Physics; Quantum dots; Testing;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
Conference_Location :
Chengdu
ISSN :
2151-7614
Print_ISBN :
978-1-4244-4712-1
Electronic_ISBN :
2151-7614
Type :
conf
DOI :
10.1109/ICBBE.2010.5516607
Filename :
5516607
Link To Document :
https://search.ricest.ac.ir/dl/search/defaultta.aspx?DTC=49&DC=3124554
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