Title :
Experimental Study on the Interaction of QDs with BSA
Author :
Liu, Kun ; Liu, Qinghua ; Xiao, Hua ; Xiong, Jianwen
Author_Institution :
Sch. of Phys. & Telecommun. Eng., South China Normal Univ., Guangzhou, China
Abstract :
The study of the interaction and the mechanism of the interaction of semiconductor quantum dots (QDs) with BSA by fluorescence spectrum. The results showed that BSA occurred static quenching within increasing concentration of QDs, the fluorescence intensity of the QDs gradually enhanced with increasing the concentration of BSA, which is because of formation of core-shell structure. The results will provide an reference for QDs toxicology in biology and medicine and the safety of treating cancer with Photodynamic Therapy (PDT).
Keywords :
bio-optics; biomedical materials; fluorescence; molecular biophysics; nanobiotechnology; proteins; radiation quenching; semiconductor quantum dots; BSA; bovine serum albumin; cancer; core-shell structure; fluorescence spectrum; photodynamic therapy; semiconductor quantum dots; static quenching; toxicology; Absorption; Buffer storage; Fluorescence; Medical treatment; Nanobioscience; Optical buffering; Physics; Quantum dots; Safety; Toxicology;
Conference_Titel :
Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
Conference_Location :
Chengdu
Print_ISBN :
978-1-4244-4712-1
Electronic_ISBN :
2151-7614
DOI :
10.1109/ICBBE.2010.5516624
