The Difference of Destruction Efficiency between Quantum Dots CdSe-PDT and CdSeS-PDT on HL60 Cells in Vitro

Author

Jiang, Fei ; Liu, Qinghua ; Wan, ChenXing ; Xiao, Hua ; Xiong, Jianwen

Author_Institution

Sch. of Phys. & Telecommun. Eng., South China Normal Univ., Guangzhou, China

fYear

2010

fDate

18-20 June 2010

Firstpage

1

Lastpage

3

Abstract

Leukemia HL60 cells are inactivated by quantum dots with the photoluminescence characteristic in vitro. The quantum dots of CdSe and CdSeS were studied at different concentrations and different light doses. The highest inactivation efficiency of CdSe-PDT runs up to 83.0%, under the condition that its concentration is 2.0μmol/ml and the light dose is 8J/cm corresponding to 410nm wavelength. However, the highest inactivation efficiency of CdSeS-PDT is just 45.9% when its concentration is 8.0μmol/ml and the light dose is 6J/cm corresponding to white light.

Keywords

II-VI semiconductors; bio-optics; cadmium compounds; cellular biophysics; photoluminescence; semiconductor quantum dots; CdSeS; HL60 cells; destruction efficiency; inactivation efficiency; leukemia; light dose; photoluminescence; quantum dot; wavelength 410 nm; Cells (biology); Electron microscopy; In vitro; Instruments; Neoplasms; Optical materials; Photoluminescence; Physics; Quantum dot lasers; Quantum dots;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on

Conference_Location

Chengdu

ISSN

2151-7614

Print_ISBN

978-1-4244-4712-1

Electronic_ISBN

2151-7614

Type

conf

DOI

10.1109/ICBBE.2010.5516631

Filename

5516631