Title :
A New Measurement to Quantity DNA Sequence and Its Application
Author :
Xie Xiaoli ; Song Shide ; Yuan Zhifa ; John, S.
Author_Institution :
Coll. of Sci., Northwest A&F Univ., Yangling, China
Abstract :
Based on distance distribution of nucleotides in a DNA sequence, a new distance measurement, average distance of four nucleotides, was proposed. The new index can be used to describe the regularity of four nucleotides distribution in a given DNA sequence. According to the new measurement, 17 complete mammal mitochondrial genomes have been analyzed and then cluster analysis and principal component analysis have been done. The results indicate that the new measurement is an efficient index to analyze DNA sequence and organic evolution.
Keywords :
DNA; genomics; DNA sequence; cluster analysis; distance distribution; mammal mitochondrial genomes; nucleotides; organic evolution; principal component analysis; Bioinformatics; DNA; Distance measurement; Educational institutions; Evolution (biology); Genomics; Nuclear measurements; Organisms; Principal component analysis; Sequences;
Conference_Titel :
Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
Conference_Location :
Chengdu
Print_ISBN :
978-1-4244-4712-1
Electronic_ISBN :
2151-7614
DOI :
10.1109/ICBBE.2010.5516793
