Title :
Screening of Antibiotic-Maggot Serum Combinations and Their Effects on Bacterial Physiology
Author :
Arora, Shuchi ; Lim Chu Sing ; Baptista, Carl
Author_Institution :
Sch. of Mech. & Aerosp. Eng., Nanyang Technol. Univ., Singapore, Singapore
Abstract :
Maggots are known for their anti-microbial properties in chronic wound healing. This paper presents research investigating the effects of maggot metabolites in combination with ciprofloxacin against Staphylococcus aureus. The screening process used was a microchannel-based separation and mixing system. The results demonstrate that for similar levels of efficacy, the partial substitution with the maggot metabolite muted the adoption of antibiotic resistance by the bacteria.
Keywords :
antibacterial activity; biochemistry; drugs; microorganisms; Staphylococcus aureus; antibiotic resistance; antibiotic-maggot serum combinations; antimicrobial properties; bacterial physiology; chronic wound healing; ciprofloxacin; maggot metabolites; maggots; microchannel mixing; microchannel-based separation; Anti-bacterial; Antibiotics; Fluids and secretions; Immune system; Medical treatment; Microchannel; Microorganisms; Physiology; Testing; Wounds;
Conference_Titel :
Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
Conference_Location :
Chengdu
Print_ISBN :
978-1-4244-4712-1
Electronic_ISBN :
2151-7614
DOI :
10.1109/ICBBE.2010.5516865
