Experimental prediction of wavelength dependence of optical path length for optical intrinsic signal analysis

Author

Sakaguchi, K. ; Furukawa, S. ; Katsura, T. ; Maki, A. ; Yamazaki, K. ; Kawaguchi, H. ; Okada, E.

Author_Institution

Dept. of Electron. & Electr. Eng., Keio Univ., Yokohama

fYear

2006

fDate

Oct. 2006

Firstpage

601

Lastpage

602

Abstract

In this study, we proposed a new method to experimentally estimate the wavelength dependence of the optical path lengths from multi-spectral images of the exposed cortex. The proposed method was applied to the path length correction for the multi-spectral measurements of the concentration changes in oxy-haemoglobin (oxy-Hb) and deoxy-haemoglobin (deoxy-Hb) in the cortical tissue of guinea pigs during auditory stimulation

Keywords

biochemistry; biomedical measurement; biomedical optical imaging; blood; brain; chemical variables measurement; molecular biophysics; neurophysiology; proteins; reflectivity; spectrochemical analysis; auditory stimulation; brain; concentration changes; cortex tissue; deoxy-haemoglobin; guinea pigs; multispectral measurement; optical intrinsic signal analysis; optical path length; oxy-haemoglobin; path length correction; reflectance; Brain modeling; Charge coupled devices; Charge-coupled image sensors; Equations; Multispectral imaging; Optical filters; Optical scattering; Reflectivity; Signal analysis; Wavelength measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Lasers and Electro-Optics Society, 2006. LEOS 2006. 19th Annual Meeting of the IEEE

Conference_Location

Montreal, Que.

Print_ISBN

0-7803-9555-7

Electronic_ISBN

0-7803-9555-7

Type

conf

DOI

10.1109/LEOS.2006.278820

Filename

4054327