Title :
Experimental prediction of wavelength dependence of optical path length for optical intrinsic signal analysis
Author :
Sakaguchi, K. ; Furukawa, S. ; Katsura, T. ; Maki, A. ; Yamazaki, K. ; Kawaguchi, H. ; Okada, E.
Author_Institution :
Dept. of Electron. & Electr. Eng., Keio Univ., Yokohama
Abstract :
In this study, we proposed a new method to experimentally estimate the wavelength dependence of the optical path lengths from multi-spectral images of the exposed cortex. The proposed method was applied to the path length correction for the multi-spectral measurements of the concentration changes in oxy-haemoglobin (oxy-Hb) and deoxy-haemoglobin (deoxy-Hb) in the cortical tissue of guinea pigs during auditory stimulation
Keywords :
biochemistry; biomedical measurement; biomedical optical imaging; blood; brain; chemical variables measurement; molecular biophysics; neurophysiology; proteins; reflectivity; spectrochemical analysis; auditory stimulation; brain; concentration changes; cortex tissue; deoxy-haemoglobin; guinea pigs; multispectral measurement; optical intrinsic signal analysis; optical path length; oxy-haemoglobin; path length correction; reflectance; Brain modeling; Charge coupled devices; Charge-coupled image sensors; Equations; Multispectral imaging; Optical filters; Optical scattering; Reflectivity; Signal analysis; Wavelength measurement;
Conference_Titel :
Lasers and Electro-Optics Society, 2006. LEOS 2006. 19th Annual Meeting of the IEEE
Conference_Location :
Montreal, Que.
Print_ISBN :
0-7803-9555-7
Electronic_ISBN :
0-7803-9555-7
DOI :
10.1109/LEOS.2006.278820
