Mathematical model for solute kinetics and body composition in hemodialysis patients

Dialysis patients with high BMI experience survival advantages as compared to dialysis patients with low BMI. Preliminary modeling results seem to confirm the dependence of survival probabilities on BMI, but also show that BMI is a too crude measure. The simulation results strongly indicate that body composition instead of BMI should be used. The purpose of this paper is to confirm this finding on the basis of concrete data concerning body composition. In addition we want to demonstrate that the clearance rate during the dialysis process and the generation rate for uremic toxins are also to be considered.