Title :
Sample Scale-Free Gene Regulatory Network Using Gene Ontology
Author :
Chen, Guanrao ; Larsen, Peter ; Almasri, Eyad ; Dai, Yang
Author_Institution :
Dept. of Comput. Sci., Illinois Univ., Chicago, IL
fDate :
Aug. 30 2006-Sept. 3 2006
Abstract :
Currently there are various approaches to the reconstruction of gene regulatory networks from different sources of data. However, none of these methods incorporates explicitly scale-free property, one of the most important features of the targeted network, into their algorithms. In this paper, several network sampling strategies are explored on a set assembled from previous published gene interactions in yeast, expecting to reconstruct regulatory networks that are scale-free
Keywords :
biology computing; genetics; microorganisms; molecular biophysics; ontologies (artificial intelligence); sampling methods; gene interactions; gene ontology; network reconstruction model; network sampling algorithm; scale-free gene regulatory network; yeast; Assembly; Bioinformatics; Cities and towns; Frequency; Fungi; Ontologies; Proteins; Sampling methods; Testing; USA Councils;
Conference_Titel :
Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE
Conference_Location :
New York, NY
Print_ISBN :
1-4244-0032-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2006.259261