Title :
Identification of Salient Patterns for Classification of Gene Expression Data
Author :
Pok, Gouchol ; Quan, Guangri ; Ryu, Keun Ho
Author_Institution :
Dept. of Comput. Sci., Yanbian Univ. of Sci. & Technol., Yanji, China
Abstract :
Identification of salient patterns for the classification of gene expression profiles is a useful step in examining the biological significance and correlation of genes with disease states. We propose a clustering-based approach in which feature selection is first carried out to identify influential genes and then salient patterns are determined to characterize each of the different classes. The proposed method has been tested with the complicated colon tumor data and the experimental results are evaluated in comparison with the published ones.
Keywords :
bioinformatics; diseases; feature extraction; genetics; molecular biophysics; pattern classification; pattern clustering; tumours; clustering-based approach; colon tumor data; disease states; feature selection; gene correlation; gene expression data; pattern classification; salient patterns; Bioinformatics; Biology; Clustering algorithms; Clustering methods; Colon; Computer science; Diseases; Gene expression; Neoplasms; Testing;
Conference_Titel :
Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
Conference_Location :
Chengdu
Print_ISBN :
978-1-4244-4712-1
Electronic_ISBN :
2151-7614
DOI :
10.1109/ICBBE.2010.5517931