Carbon Nanopowder Binds with DNA and May Induce DNA Aggregation

The interaction between nanomaterials and genomes is getting more and more attention. Such studies are getting involved into several fields: environment safety, food safety, nanobiotechnology and drug development. Direct interaction between nanoparticles and DNA in vitro has been reported in several studies, but data for in vivo binding between genomic DNA and nanoparticles are rare. In this study, we presented that carbon nanopowder (CNP) is able to bind with DNA both in vitro and in vivo. Interestingly, CNP binds to DNA with a relatively high density and may induce DNA aggregation.