Title :
Development and Evaluation of a High Performance Micro-CT System for Insect or Small Animal Imaging
Author :
Gui, Jianbao ; Zou, Jing ; Rong, Junyan ; Hu, Zhanli ; Li, Yanming ; Xi, Dongxing ; Zheng, Hairong
Author_Institution :
Paul C. Lauterbur Res. Center for Biomed. Imaging, Chinese Acad. of Sci., Shenzhen, China
Abstract :
A high performance micro-tomography (micro-CT) system for insect or small animal imaging has been developed. The system consists of an x-ray source with small focus spot and high brightness, a high precision rotation stage with an object chuck to achieve a cone-beam mode scan, and an x-ray imaging detector. The core of the system is a cooled x-ray imaging detector with high spatial resolution, high sensitivity and ultra-low noise. Since imaging performance of the detector is mostly responsible for the resultant image quality and eventually determines the quality of a tomogram, we have evaluated the imaging characteristics of the detector in terms of modulation-transfer function (MTF), noise-power spectrum (NPS) and give some high quality x-ray digital radiation (DR) and 3D rendered CT images of some insects and a small fish.
Keywords :
X-ray apparatus; X-ray detection; biomedical equipment; computerised tomography; optical transfer function; 3D rendered CT images; X-ray source; cone beam mode scan; cooled X-ray imaging detector; detector imaging performance; high performance microCT system; high precision rotation stage; image quality; insect imaging; microtomography system; modulation transfer function; noise-power spectrum; object chuck; small animal imaging; tomogram quality; Animals; Brightness; Focusing; High-resolution imaging; Insects; Optical imaging; Radiation detectors; X-ray detection; X-ray detectors; X-ray imaging;
Conference_Titel :
Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
Conference_Location :
Chengdu
Print_ISBN :
978-1-4244-4712-1
Electronic_ISBN :
2151-7614
DOI :
10.1109/ICBBE.2010.5518148