Observation of Hydrofluoric Acid Burns on Osseous Tissues by Means of Terahertz Spectroscopic Imaging

Author

Baughman, W.E. ; Yokus, H. ; Balci, Sinan ; Wilbert, David S. ; Kung, Peter ; Kim, Song Min

Author_Institution

Dept. of Electr. & Comput. Eng., Univ. of Alabama, Tuscaloosa, AL, USA

Volume

17

Issue

4

fYear

2013

fDate

Jul-13

Firstpage

798

Lastpage

805

Abstract

Terahertz technologies have gained great amount of attention for biomedical imaging and tissue analysis. In this study, we utilize terahertz imaging to study the effects of hydrofluoric acid on both compact bone tissue and cartilage. We compare the differences observed in the exposure for formalin fixed and raw, dried, tissue as well as those resulting from a change in hydrofluoric (HF) concentration. Measurements are performed with THz-TDS, and a variety of spectroscopic-based image reconstruction techniques are utilized to develop contrast in the features of interest.

Keywords

biochemistry; bone; image reconstruction; medical image processing; terahertz wave imaging; HF; THz-TDS; biomedical imaging; bone cartilage; bone tissue; hydrofluoric acid; hydrofluoric concentration; osseous tissues; spectroscopic-based image reconstruction; terahertz spectroscopic imaging; tissue analysis; Absorption; Biomedical imaging; Bones; Delay; Image reconstruction; Time domain analysis; Biomedical imaging; hydrofluoric acid; osseous tissue; terahertz (THz) time-domain spectroscopy; terahertz spectroscopic imaging;

fLanguage

English

Journal_Title

Biomedical and Health Informatics, IEEE Journal of

Publisher

ieee

ISSN

2168-2194

Type

jour

DOI

10.1109/JBHI.2013.2243158

Filename

6422316