Digoxin induced changes in the distribution of fast heart rate episodes during paroxysmal atrial fibrillation

Author

Hnatkova, K. ; Murgatroyd, FD ; Alferness, CA ; Camm, AJ ; Malik, M.

Author_Institution

Dept. of Cardiological Sci., St. George´´s Hospital Med. Sch., London, UK

fYear

1995

fDate

10-13 Sept. 1995

Firstpage

181

Lastpage

184

Abstract

This study investigated AF episodes with RR intervals shorter than a given limit (i.e. defibrillator waiting times) in 24-hour Holter tapes recorded during a cross-over trial of Placebo and Digoxin treatment of patients with paroxysmal AF. 25 tapes with AF episodes of at least 1000 ventricular cycles were selected (14 recorded on Placebo, and 11 on Digoxin). For each tape, the mean and maximum duration of AF episodes with all RR intervals700 ms. There were, however, strongly significant differences (p<10/sup -4/-10/sup -7/) between the maximum waiting times which were longer with Placebo.

Keywords

defibrillators; electrocardiography; patient monitoring; patient treatment; 24 h; 24-hour Holter tapes; 400 to 1000 ms; Digoxin induced changes; Digoxin treatment; Placebo; RR intervals; Wilcoxon test; cross-over trial; defibrillator waiting times; fast heart rate episodes; maximum waiting times; mean waiting times; paroxysmal AF; paroxysmal atrial fibrillation; thresholds; Atrial fibrillation; Cardiology; Defibrillation; Electric shock; Heart rate; Hospitals; Immune system; Medical treatment; Safety devices; Testing;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology 1995

Conference_Location

Vienna, Austria

Print_ISBN

0-7803-3053-6

Type

conf

DOI

10.1109/CIC.1995.482602

Filename

482602