DocumentCode :
3171827
Title :
Right ventricular wall mechanics in normals and patients with pulmonary hypertension using magnetic resonance tissue tagging
Author :
Fayad, Zahi A. ; Ferrari, Victor A. ; Kraitchman, Dara L. ; Young, Alistair A. ; Bloomgarden, Daniel C. ; Axel, Leon
Author_Institution :
Pennsylvania Univ., Philadelphia, PA, USA
fYear :
1995
fDate :
10-13 Sept. 1995
Firstpage :
233
Lastpage :
236
Abstract :
Right ventricular hypertrophy (RVH) and RV dysfunction are difficult to evaluate due to the complex shape of the RV and prognostic limitations of conventional global function parameters. We used MRI with magnetization tagging to measure 2-D systolic motion and deformation of the right ventricular free wall (RVFW) and septum (SEPT) in 5 patients with RVH secondary to pulmonary hypertension, and 12 normal volunteers (NL). Regional displacement (D) and 2-D principal strains in the short-axis plane were averaged at basal, midventricular and apical levels. SEPT D was severely decreased at all levels in RVH vs. NL (P<0.005). In RVH, RVFW D was higher than SEPT D (P<0.02). The 2-D strains were reduced in SEPT at all levels in RVH vs. NL (P<0.05). This technique may permit the study of progression and regression of RVH in various disease states.
Keywords :
biomagnetism; biomechanics; biomedical NMR; cardiology; image segmentation; image sequences; magnetisation; medical image processing; muscle; 2-D principal strains; 2-D systolic motion; MRI; RV dysfunction; apical levels; basal levels; complex shape; disease states; magnetic resonance tissue tagging; magnetization tagging; midventricular levels; normals; patients; prognostic limitations; pulmonary hypertension; regional displacement; right ventricular hypertrophy; right ventricular wall mechanics; septum; short-axis plane; Capacitive sensors; Cardiac disease; Cardiovascular diseases; Echocardiography; Hypertension; Magnetic resonance imaging; Magnetization; Myocardium; Shape; Tagging;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Computers in Cardiology 1995
Conference_Location :
Vienna, Austria
Print_ISBN :
0-7803-3053-6
Type :
conf
DOI :
10.1109/CIC.1995.482615
Filename :
482615
Link To Document :
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