Title :
Analyzing cardiovascular variabilities in patients with heart failure
Author :
Voss, A. ; Schroeder, R. ; Baumert, M. ; Truebner, S. ; Goernig, M. ; Hagenow, A. ; Figulla, Hr
Author_Institution :
Dept. of Med. Eng., Univ. of Appl. Sci. Jena
Abstract :
Nearly 60% of patients with heart failure (HF) suffer from cardiac death within five years after diagnosis. Strategies for early diagnosis of CHF are rather insufficient. Therefore, the objective of this study was to develop a parameter set for an enhanced risk stratification in HF patients. From 43 patients suffering from HF (NYHAgesII, EF<45%) and from 20 healthy subjects (REF) heart sound (HS), heart rate and blood pressure variability (HRV and BPV), interactions between heart rate and blood pressure (joint symbolic dynamics-JSD) and blood pressure morphology (BPM) were analyzed. Measures from BPV, BPM and JSD revealed high significances (p<0.0001) discriminating REF and HF. A set of three parameters from HS, JSD and BPM was developed (sensitivity=91.7%, specificity=93.3%) for risk stratification in patients with heart failure
Keywords :
biomedical measurement; cardiovascular system; haemodynamics; patient diagnosis; HRV; blood pressure morphology; blood pressure variability; cardiac death; cardiovascular variability; healthy subjects; heart failure patients; heart rate; heart sound; joint symbolic dynamics; risk analysis; Biomedical monitoring; Blood pressure; Blood pressure variability; Cardiology; Electrocardiography; Failure analysis; Hafnium; Heart rate; Heart rate variability; Medical diagnostic imaging;
Conference_Titel :
Computers in Cardiology, 2005
Conference_Location :
Lyon
Print_ISBN :
0-7803-9337-6
DOI :
10.1109/CIC.2005.1588090
