Title :
Multivariate Skew t Mixture Models: Applications to Fluorescence-Activated Cell Sorting Data
Author :
Wang, Kui ; Ng, Shu-Kay ; McLachlan, Geoffrey J.
Author_Institution :
Dept. of Math., Univ. of Queensland, St. Lucia, QLD, Australia
Abstract :
In many applied problems in the context of pattern recognition, the data often involve highly asymmetric observations. Normal mixture models tend to overfit when additional components are included to capture the skewness of the data. Increased number of pseudo-components could lead to difficulties and inefficiencies in computations. Also, the contours of the fitted mixture components may be distorted. In this paper, we propose to adopt mixtures of multivariate skew t distributions to handle highly asymmetric data. The EM algorithm is used to compute the maximum likelihood estimates of model parameters. The method is illustrated using a flurorescence-activated cell sorting data.
Keywords :
expectation-maximisation algorithm; pattern recognition; sorting; EM algorithm; data skewness; fitted mixture components; fluorescence-activated cell sorting data; highly asymmetric observations; maximum likelihood estimates; multivariate skew t mixture models; pattern recognition; pseudo-components; Context modeling; Covariance matrix; Digital images; Fluorescence; Mathematics; Maximum likelihood estimation; Parameter estimation; Pattern recognition; Robustness; Sorting; Asymmetric multivariate data; EM algorithm; fluorescence-activated cell sorting; mixture models; skewed t;
Conference_Titel :
Digital Image Computing: Techniques and Applications, 2009. DICTA '09.
Conference_Location :
Melbourne, VIC
Print_ISBN :
978-1-4244-5297-2
Electronic_ISBN :
978-0-7695-3866-2
DOI :
10.1109/DICTA.2009.88