• DocumentCode
    3178180
  • Title

    Multivariate Skew t Mixture Models: Applications to Fluorescence-Activated Cell Sorting Data

  • Author

    Wang, Kui ; Ng, Shu-Kay ; McLachlan, Geoffrey J.

  • Author_Institution
    Dept. of Math., Univ. of Queensland, St. Lucia, QLD, Australia
  • fYear
    2009
  • fDate
    1-3 Dec. 2009
  • Firstpage
    526
  • Lastpage
    531
  • Abstract
    In many applied problems in the context of pattern recognition, the data often involve highly asymmetric observations. Normal mixture models tend to overfit when additional components are included to capture the skewness of the data. Increased number of pseudo-components could lead to difficulties and inefficiencies in computations. Also, the contours of the fitted mixture components may be distorted. In this paper, we propose to adopt mixtures of multivariate skew t distributions to handle highly asymmetric data. The EM algorithm is used to compute the maximum likelihood estimates of model parameters. The method is illustrated using a flurorescence-activated cell sorting data.
  • Keywords
    expectation-maximisation algorithm; pattern recognition; sorting; EM algorithm; data skewness; fitted mixture components; fluorescence-activated cell sorting data; highly asymmetric observations; maximum likelihood estimates; multivariate skew t mixture models; pattern recognition; pseudo-components; Context modeling; Covariance matrix; Digital images; Fluorescence; Mathematics; Maximum likelihood estimation; Parameter estimation; Pattern recognition; Robustness; Sorting; Asymmetric multivariate data; EM algorithm; fluorescence-activated cell sorting; mixture models; skewed t;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Digital Image Computing: Techniques and Applications, 2009. DICTA '09.
  • Conference_Location
    Melbourne, VIC
  • Print_ISBN
    978-1-4244-5297-2
  • Electronic_ISBN
    978-0-7695-3866-2
  • Type

    conf

  • DOI
    10.1109/DICTA.2009.88
  • Filename
    5384898