Title :
Automatic analysis of Categorical Verbal Fluency for Mild Cognitive impartment detection: A non-linear language independent approach
Author :
Lopez-de-Ipina, K. ; Martinez-de-Lizarduy, U. ; Barroso, N. ; Ecay-Torres, M. ; Martinez-Lage, P. ; Torres, F. ; Faundez-Zanuy, Marcos
Author_Institution :
Eng. Sch., Univ. del País Vasco, Donostia-San Sebastian, Spain
Abstract :
Alzheimer´s disease (AD) is one of the main causes of dementia in the world and the patients develop severe disability and sometime full dependence. In previous stages Mild Cognitive Impairment (MCI) produces cognitive loss but not severe enough to interfere with daily life. This work, on selection of biomarkers from speech for the detection of AD, is part of a wide-ranging cross study for the diagnosis of Alzheimer. Specifically in this work a task for detection of MCI has been used. The task analyzes Categorical Verbal Fluency. The automatic classification is carried out by SVM over classical linear features, Castiglioni fractal dimension and Permutation Entropy. Finally the most relevant features are selected by ANOVA test.
Keywords :
cognition; entropy; feature selection; fractals; medical disorders; patient diagnosis; speech; speech processing; statistical analysis; support vector machines; ANOVA test; Alzheimer disease diagnosis; Castiglioni fractal dimension; automatic categorical verbal fluency analysis; biomarker selection; dementia; feature selection; linear features; mild cognitive impartment detection; nonlinear language independent approach; permutation entropy; speech; support vector machine; Analysis of variance; Dementia; Fractals; Speech; Support vector machines; Alzheimer´s Disease; Automatic speech analysis; Entropy; Fractals; Mild Cognitive Impairment; Non.linear features; automatic selection of features;
Conference_Titel :
Bioinspired Intelligence (IWOBI), 2015 4th International Work Conference on
Conference_Location :
San Sebastian
Print_ISBN :
978-1-4673-7845-1
DOI :
10.1109/IWOBI.2015.7160151