• DocumentCode
    3187194
  • Title

    Data Storage and Analysis system for conducting Biotechnological Experiments

  • Author

    Spahic, Damir ; Mausa, Goran ; Pavelic, Sandra Kraljevic ; Grbac, Tihana Galinac

  • Author_Institution
    Fac. of Eng., Univ. of Rijeka, Rijeka, Croatia
  • fYear
    2015
  • fDate
    25-29 May 2015
  • Firstpage
    470
  • Lastpage
    475
  • Abstract
    Biomedical research, such as analyses of antiproliferative properties of certain compounds designed to target various human cancer cells, often requires extensive preclinical evaluation to obtain conclusive evidence. The first step in biological evaluation is typically very rigorous in comparing different compounds´ concentrations on a number of target cells in vitro. Therefore, the experiments yield a set of data that needs to be properly documented, classified, stored and analyzed. This paper presents the Data Storage and Analysis System designed to make that process simpler, faster and less prone to human errors. The importance of such research and its implications lead to high sensitivity to bias. Our system minimizes the chance for human error in the process of data transfer by making the process as automatic as possible and allowing the posterior validation of data by the lead researchers. The analysis most often requires both numerical calculations, such as the IC50 value, and graphical visualization of compounds´ performances. The system offers to researchers a simple interface for simultaneous comparison of results by choosing the appropriate combination of a compound, target cells and date of experiments.
  • Keywords
    bioinformatics; biotechnology; cellular biophysics; data visualisation; graphical user interfaces; IC50 value; antiproliferative property analysis; biological evaluation; biomedical research; biotechnological experiments; compound concentration; data analysis; data analysis system; data classification; data documentation; data storage; data storage system; data transfer process; graphical visualization; human cancer cells; posterior data validation; preclinical evaluation; sensitivity analysis; target cells; Compounds; Data analysis; Databases; In vitro; Memory; Servers; Standards; data analysis; data storage; visualization;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Information and Communication Technology, Electronics and Microelectronics (MIPRO), 2015 38th International Convention on
  • Conference_Location
    Opatija
  • Type

    conf

  • DOI
    10.1109/MIPRO.2015.7160317
  • Filename
    7160317