Title :
The feasibility study on 3-dimensional fluorescent x-ray computed tomography using the pinhole effect for biomedical applications
Author :
Sunaguchi, Naoki ; Yuasa, Takeshi ; Hyodo, Kazuyuki ; Zeniya, Tsutomu
Author_Institution :
Grad. Sch. of Eng., Gunma Univ., Kiryu, Japan
Abstract :
We propose a 3-dimensional fluorescent x-ray computed tomography (CT) pinhole collimator, aimed at providing molecular imaging with quantifiable measures and sub-millimeter spatial resolution. In this study, we demonstrate the feasibility of this concept and investigate imaging properties such as spatial resolution, contrast resolution and quantifiable measures, by imaging physical phantoms using a preliminary imaging system developed with monochromatic synchrotron x rays constructed at the BLNE-7A experimental line at KEK, Japan.
Keywords :
biomedical optical imaging; collimators; computerised tomography; diagnostic radiography; fluorescence; medical image processing; phantoms; 3-dimensional fluorescent X-ray computed tomography; BL E-7A experimental line; biomedical applications; contrast resolution; imaging properties; molecular imaging; monochromatic synchrotron X rays; physical phantoms; pinhole collimator; pinhole effect; preliminary imaging system; spatial resolution; submillimeter spatial resolution; Charge coupled devices; Fluorescence; Image reconstruction; Imaging; Photonics; Spatial resolution; X-ray imaging;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE
Conference_Location :
Osaka
DOI :
10.1109/EMBC.2013.6610009
