• DocumentCode
    319830
  • Title

    Model analysis of the interaction between perfusion pressure, MVO 2 and coronary flow control

  • Author

    Dankelman, J. ; Spaan, J.A.E.

  • Author_Institution
    Fac. of Mech. Eng. & Marine Technol., Delft Univ. of Technol., Netherlands
  • Volume
    4
  • fYear
    1996
  • fDate
    31 Oct-3 Nov 1996
  • Firstpage
    1748
  • Abstract
    Changes in coronary perfusion pressure affect coronary arterial resistance (autoregulation) as well as myocardial oxygen consumption (Gregg´s phenomenon). The interaction between the effects of perfusion pressure and myocardial oxygen consumption on coronary flow control was investigated using a model. This model analysis predicts that autoregulation and Gregg´s phenomenon compete with each other in controlling coronary flow. The negative feedback system of the metabolic control system can become a positive feedback system when the level of arterial tone decreases and Gregg´s phenomenon becomes more important
  • Keywords
    cardiology; feedback; flow control; haemorheology; oxygen; physiological models; Gregg´s phenomenon; O2; arterial tone level; autoregulation; coronary flow control; metabolic control system; model analysis; myocardial oxygen consumption; negative feedback system; perfusion pressure; positive feedback system; Blood flow; Control systems; Electrical resistance measurement; Heart; Immune system; Marine technology; Mechanical variables measurement; Myocardium; Negative feedback; Pressure control;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE
  • Conference_Location
    Amsterdam
  • Print_ISBN
    0-7803-3811-1
  • Type

    conf

  • DOI
    10.1109/IEMBS.1996.647643
  • Filename
    647643
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=319830