Real-time cardiorespiratory coherence is blind to changes in respiration during general anesthesia

Author

Brouse, Chris J. ; Dumont, Guy A. ; Myers, Dorothy ; Cooke, E. ; Stinson, J. ; Lim, Jungyoul ; Ansermino, J. Mark

Author_Institution

Dept. of Electr. & Comput. Eng., Univ. of British Columbia, Vancouver, BC, Canada

fYear

2013

fDate

3-7 July 2013

Firstpage

5360

Lastpage

5364

Abstract

Purpose. A novel real-time cardiorespiratory coherence (CRC) algorithm has been developed to monitor nociception during general anesthesia. CRC uses custom designed filters to track and analyze the respiratory sinus arrhythmia (RSA) as it moves in time and frequency. CRC is a form of sensor fusion between heart rate and respiration, estimating the strength of linear coupling between the two signals. The aim of this study was to estimate the effect of changes in respiration rate (RR) and peak airway pressure (PPaw) on CRC. The response of CRC was compared to a prior offline wavelet-based algorithm (WTCRC) as well as traditional univariate heart rate variability (HRV) measures. A nociception index was created for each algorithm, ranging from 0 (no nociception) to 100 (strong nociception).

Keywords

cardiology; drugs; mechanoception; medical signal processing; patient monitoring; pneumodynamics; real-time systems; CRC filter; CRC response; HRV measurement; RSA; WTCRC algorithm; general anesthesia; heart rate signal; linear coupling strength; nociception index; nociception monitoring; offline wavelet-based algorithm; peak airway pressure change effect; real-time cardiorespiratory coherence algorithm; respiration change; respiration rate change effect; respiration signal; respiratory sinus arrhythmia; univariate heart rate variability measurement; Anesthesia; Coherence; Frequency-domain analysis; Heart rate variability; Indexes; Monitoring; Real-time systems;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE

Conference_Location

Osaka

ISSN

1557-170X

Type

conf

DOI

10.1109/EMBC.2013.6610760

Filename

6610760