• DocumentCode
    3208926
  • Title

    Toxicity study of Schiff bases derived from 2,6-diaminopyridine and their novel metal complexes

  • Author

    Fadzel, Fatimatuzzahraa Mohd ; Bahron, Hadariah ; Kassim, Karimah ; Zain, Mazatulikhma Mat

  • Author_Institution
    Faculty of Applied Sciences, Universiti Teknologi MARA, UiTM, Shah Alam, Selangor, Malaysian
  • fYear
    2010
  • fDate
    5-7 Dec. 2010
  • Firstpage
    757
  • Lastpage
    761
  • Abstract
    Two Schiff bases (L1∶C19H15N3O2 and L3∶C21H19N3O6) derived from 2,6-diaminopyridine with salicylaldehyde and o-vanillin, respectively, were successfully synthesized and characterized. Four novel metal complexes of these ligands with Zn(II) and Cd(II) namely ZnL1, ZnL3, CdL1 and CdL3 were obtained and the chemical structures were investigated by means of elemental analysis, FTIR, conductivity and magnetic susceptibility measurements. All the complexes were diamagnetic, displayed ν(C=N) bands in the range 1599–1615 cm−1 and non-electrolytic in solution. The toxicity of the Schiff base ligands and their novel metal complexes was studied from the viability of treated human neuroblastoma SH-SY5Y cell lines.
  • Keywords
    Biology; Compounds; Ethanol; Ions; Magnetic susceptibility; Zinc; 2,6-diaminopyridine; Schiff bases; ligands; novel metal complexes;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Science and Social Research (CSSR), 2010 International Conference on
  • Conference_Location
    Kuala Lumpur, Malaysia
  • Print_ISBN
    978-1-4244-8987-9
  • Type

    conf

  • DOI
    10.1109/CSSR.2010.5773885
  • Filename
    5773885
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=3208926