Title :
Blood withdrawal system for continuous ex vivo glucose and lactate monitoring
Author :
Gfrerer, R.J. ; Trajanoski, Z. ; Skraba, F. ; Jobst, G. ; Urban, G. ; Otanko, P.K. ; Wach, P.
Author_Institution :
Dept. of Biophys., Tech. Univ. Graz, Austria
fDate :
31 Oct-3 Nov 1996
Abstract :
The objective of the study was to develop a measurement system for blood glucose and lactate and to evaluate a portable blood withdrawal system. For the blood withdrawal system a double lumen catheter was used. The inner lumen of the catheter was perfused with heparin solution and the outer lumen was used to collect the blood samples into 56 vacuum tubes at variable volumes and time intervals. A sensor flow chamber incorporating a thin-film amperometric glucose/lactate sensor was connected to the blood withdrawal system. The device was evaluated in 10 clinical experiments which demonstrated the stability of the sensors during a 6 hour period. In conclusion, on-line ex vivo glucose and lactate monitoring in blood is feasible with a portable blood withdrawal system
Keywords :
biomedical equipment; blood; chemical analysis; organic compounds; patient monitoring; 6 h; clinical experiments; continuous ex vivo glucose monitoring; heparin solution; lactate monitoring; medical instrumentation; portable blood withdrawal system; sensor flow chamber; sensor stability; thin-film amperometric glucose/lactate sensor; vacuum tubes; Biomembranes; Biosensors; Blood; Catheters; Data acquisition; Electron tubes; Monitoring; Sensor systems; Sugar; Thin film sensors;
Conference_Titel :
Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE
Conference_Location :
Amsterdam
Print_ISBN :
0-7803-3811-1
DOI :
10.1109/IEMBS.1996.656853
