Title :
A multiwavelength VIS-NIR spectrometer for pulsatile measurement of hemoglobin derivatives in whole blood
Author :
Mendelson, Yitzhak
Author_Institution :
Dept. of Biomed. Eng., Worcester Polytech. Inst., MA, USA
fDate :
31 Oct-3 Nov 1996
Abstract :
Describes a pulsatile multiwavelength visible-near infrared spectrometer system for investigating the possibility of measuring selected hemoglobin derivatives in flowing whole blood. The system, which is based on a compact size diode array spectrometer, is designed to acquire the pulsatile and non-pulsatile components of the photoplethysmogram from a peripheral vascular tissue bed. The system was evaluated in a series of in vitro studies to assess the feasibility of monitoring simultaneously arterial blood oxygen saturation, carboxyhemoglobin, and methemoglobin
Keywords :
biomedical equipment; biomedical measurement; blood; infrared spectrometers; molecular biophysics; proteins; visible spectrometers; O2; arterial blood oxygen saturation; carboxyhemoglobin; hemoglobin derivatives; in vitro studies; medical instrumentation; methemoglobin; multiwavelength VIS-NIR spectrometer; peripheral vascular tissue bed; photoplethysmogram; pulsatile measurement; whole blood; Absorption; Blood; Circuit simulation; Fingers; Holography; Imaging phantoms; Light sources; Optical filters; Photodetectors; Spectroscopy;
Conference_Titel :
Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE
Conference_Location :
Amsterdam
Print_ISBN :
0-7803-3811-1
DOI :
10.1109/IEMBS.1996.656883
