Simulation of comparative thresholds for neural and cardiac tissue

Author

Evans, Frank ; Plonsey, Robert

Author_Institution

Dept. of Biomed. Eng., Duke Univ., Durham, NC, USA

Volume

1

fYear

1996

fDate

31 Oct-3 Nov 1996

Firstpage

321

Abstract

It is well-known that neural tissue is more excitable than cardiac tissue. The source of the disparity appears to be less well-known. Membrane and fiber simulations, using the Chiu-Sweeney nerve model and the Ebihara-Johnson, Beeler-Reuter cardiac model, suggest that the myelinated structure-rather than membrane kinetics alone-is responsible for the greater excitability of neural tissue

Keywords

bioelectric phenomena; biomembranes; cardiology; neurophysiology; physiological models; Beeler-Reuter cardiac model; Chiu-Sweeney nerve model; Ebihara-Johnson cardiac model; cardiac tissue; comparative thresholds simulation; excitability; extracellular stimulation; membrane kinetics; membrane patch simulation; myelinated structure; neural tissue; resting membrane voltage; strength-duration curves; Biomedical engineering; Biomembranes; Cardiac tissue; Coils; Conductivity; Kinetic theory; Magnetic stimulation; Nerve fibers; Optical fiber cables; Prototypes;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE

Conference_Location

Amsterdam

Print_ISBN

0-7803-3811-1

Type

conf

DOI

10.1109/IEMBS.1996.656973

Filename

656973