Title :
Simulation of comparative thresholds for neural and cardiac tissue
Author :
Evans, Frank ; Plonsey, Robert
Author_Institution :
Dept. of Biomed. Eng., Duke Univ., Durham, NC, USA
fDate :
31 Oct-3 Nov 1996
Abstract :
It is well-known that neural tissue is more excitable than cardiac tissue. The source of the disparity appears to be less well-known. Membrane and fiber simulations, using the Chiu-Sweeney nerve model and the Ebihara-Johnson, Beeler-Reuter cardiac model, suggest that the myelinated structure-rather than membrane kinetics alone-is responsible for the greater excitability of neural tissue
Keywords :
bioelectric phenomena; biomembranes; cardiology; neurophysiology; physiological models; Beeler-Reuter cardiac model; Chiu-Sweeney nerve model; Ebihara-Johnson cardiac model; cardiac tissue; comparative thresholds simulation; excitability; extracellular stimulation; membrane kinetics; membrane patch simulation; myelinated structure; neural tissue; resting membrane voltage; strength-duration curves; Biomedical engineering; Biomembranes; Cardiac tissue; Coils; Conductivity; Kinetic theory; Magnetic stimulation; Nerve fibers; Optical fiber cables; Prototypes;
Conference_Titel :
Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE
Conference_Location :
Amsterdam
Print_ISBN :
0-7803-3811-1
DOI :
10.1109/IEMBS.1996.656973