Title :
Effects of tissue electrical properties on neural excitation
Author :
Grill, Warren M.
Author_Institution :
Dept. of Biomed. Eng., Case Western Reserve Univ., Cleveland, OH, USA
fDate :
31 Oct-3 Nov 1996
Abstract :
The influence of anisotropy and inhomogeneity of tissue electrical conductivity on the relationship between the threshold current and the electrode-to-fiber distance was determined by computer simulation. Anisotropy affected both the slope and offset of the current-distance curve. Inhomogeneity also affected the slope and offset of the current-distance curves, and in some cases caused reversals in recruitment order. This study demonstrates the importance of accurate representation of tissue electrical properties when modeling extracellular electrical stimulation
Keywords :
bioelectric phenomena; cellular biophysics; digital simulation; neurophysiology; patient treatment; physiological models; computer simulation; current-distance curve; electrode-to-fiber distance; extracellular electrical stimulation modeling; neural excitation; recruitment order reversals; threshold current; tissue electrical properties effects; tissue electrical properties representation; Anisotropic magnetoresistance; Biological system modeling; Biological tissues; Conductivity; Electrical stimulation; Electrodes; Nerve fibers; Power system modeling; Predictive models; Threshold current;
Conference_Titel :
Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE
Conference_Location :
Amsterdam
Print_ISBN :
0-7803-3811-1
DOI :
10.1109/IEMBS.1996.656987
