Single cell volume measurement using a computer controlled patch-clamp electrode displacement

Author

Asfour, Makdam ; Novakov, Emile ; Gumery, Pierre-yves ; Verdetti, Jean ; Queyroy, Alain

Author_Institution

Lab. d´´Instrum. Micro-Inf. et Electron., Univ. Joseph Fourier, Grenoble, France

Volume

1

fYear

1996

fDate

31 Oct-3 Nov 1996

Firstpage

381

Abstract

Using a hydraulic micromanipulator, the authors have developed a new instrument to pilot precisely the displacement of a patch-electrode via a PC. The aim of this instrument is to measure the changes of the height of a single cell in culture using the same equipment as for the patch-clamp technique

Keywords

biological techniques; biology computing; cellular biophysics; computerised instrumentation; electrodes; manipulators; microcomputer applications; volume measurement; biological research technique; cell volume regulation; computer controlled patch-clamp electrode displacement; hydraulic micromanipulator; single cell height changes; single cell volume measurement; Control systems; Couplings; Displacement control; Electrodes; Instruments; Microelectrodes; Micromanipulators; Micromotors; Vibrations; Volume measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE

Conference_Location

Amsterdam

Print_ISBN

0-7803-3811-1

Type

conf

DOI

10.1109/IEMBS.1996.657003

Filename

657003