Title :
Single cell volume measurement using a computer controlled patch-clamp electrode displacement
Author :
Asfour, Makdam ; Novakov, Emile ; Gumery, Pierre-yves ; Verdetti, Jean ; Queyroy, Alain
Author_Institution :
Lab. d´´Instrum. Micro-Inf. et Electron., Univ. Joseph Fourier, Grenoble, France
fDate :
31 Oct-3 Nov 1996
Abstract :
Using a hydraulic micromanipulator, the authors have developed a new instrument to pilot precisely the displacement of a patch-electrode via a PC. The aim of this instrument is to measure the changes of the height of a single cell in culture using the same equipment as for the patch-clamp technique
Keywords :
biological techniques; biology computing; cellular biophysics; computerised instrumentation; electrodes; manipulators; microcomputer applications; volume measurement; biological research technique; cell volume regulation; computer controlled patch-clamp electrode displacement; hydraulic micromanipulator; single cell height changes; single cell volume measurement; Control systems; Couplings; Displacement control; Electrodes; Instruments; Microelectrodes; Micromanipulators; Micromotors; Vibrations; Volume measurement;
Conference_Titel :
Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE
Conference_Location :
Amsterdam
Print_ISBN :
0-7803-3811-1
DOI :
10.1109/IEMBS.1996.657003