A pruned ensemble classifier for effective breast thermogram analysis

Thermal infrared imaging has been shown to be useful for diagnosing breast cancer, since it is able to detect small tumors and hence can lead to earlier diagnosis. In this paper, we present a computer-aided diagnosis approach for analysing breast thermograms. We extract image features that describe bilateral differences of the breast regions in the thermogram, and then feed these features to an ensemble classifier. For the classification, we present an extension to the Under-Sampling Balanced Ensemble (USBE) algorithm. USBE addresses the problem of imbalanced class distribution that is common in medical decision making by training different classifiers on different subspaces, where each subspace is created so as to resemble a balanced classification problem. To combine the individual classifiers, we use a neural fuser based on discriminants and apply a classifier selection procedure based on a pairwise double-fault diversity measure to discard irrelevant and similar classifiers. We demonstrate that our approach works well, and that it statistically outperforms various other ensemble approaches including the original USBE algorithm.